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Unraveling the Brain's Dynamic Architecture

Exploring the neural mechanisms of learning, memory, and disease across scales.

Our lab focuses on understanding how the brain alters its structure and function in learning, aging, and psychiatric disorders, across its organizational hierarchy from synapses to functional networks.

Dr. Ju Lu

Ju Lu

Principal Investigator

Research Area 1: Impact of Chronic Stress on Mouse Neural Circuits and Behavior

Research Area 1: Impact of Chronic Stress on Mouse Neural Circuits and Behavior

We study how chronic stress, a major risk factor for psychiatric disorders including depression and anxiety, disrupts the synaptic circuit and affects animal behavior. We combine advanced in vivo two-photon imaging of structural and functional changes in the mouse brain with genetic, pharmacological, chemogenetic, and behavioral manipulations. We are also interested in the therapeutic potential of novel psychoactive substances in stress-associated psychiatric disorders.

Join the Lab

Lehigh University Campus

We are always looking for motivated undergraduate and graduate students, as well as postdoctoral researchers, to join our team. If you are passionate about neuroscience and interested in our research, please reach out!

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Publications

Explore our latest research findings and publications.

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